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Qun Chen Selected Research

Amobarbital (Amsal)

1/2018Intermediary metabolism and fatty acid oxidation: novel targets of electron transport chain-driven injury during ischemia and reperfusion.
6/2013Cardioprotection by modulation of mitochondrial respiration during ischemia-reperfusion: role of apoptosis-inducing factor.
9/2012Blockade of electron transport before ischemia protects mitochondria and decreases myocardial injury during reperfusion in aged rat hearts.
1/2012Postconditioning modulates ischemia-damaged mitochondria during reperfusion.
5/2009Reversible blockade of electron transport with amobarbital at the onset of reperfusion attenuates cardiac injury.
2/2008Ischemic defects in the electron transport chain increase the production of reactive oxygen species from isolated rat heart mitochondria.
1/2008Inhibited mitochondrial respiration by amobarbital during cardiac ischaemia improves redox state and reduces matrix Ca2+ overload and ROS release.
12/2006Reversible blockade of electron transport during ischemia protects mitochondria and decreases myocardial injury following reperfusion.
1/2006Blockade of electron transport before cardiac ischemia with the reversible inhibitor amobarbital protects rat heart mitochondria.

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Qun Chen Research Topics

Disease

52Neoplasms (Cancer)
06/2022 - 07/2002
47Ischemia
12/2022 - 06/2002
21Infarction (Infarctions)
01/2022 - 03/2002
16Mitochondrial Diseases (Mitochondrial Disease)
01/2022 - 07/2004
13Inflammation (Inflammations)
07/2022 - 10/2010
9Pancreatic Neoplasms (Pancreatic Cancer)
06/2022 - 11/2007
9Reperfusion Injury
01/2022 - 07/2002
8Fibrosis (Cirrhosis)
01/2022 - 06/2004
7Myocardial Ischemia (Ischemic Heart Diseases)
01/2022 - 09/2003
7Adenocarcinoma
08/2021 - 05/2014
6Spinal Cord Injuries (Spinal Cord Injury)
01/2022 - 11/2017
6Hypoxia (Hypoxemia)
01/2022 - 08/2002
6Necrosis
05/2011 - 10/2002
6Prostatic Neoplasms (Prostate Cancer)
12/2007 - 10/2002
5Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2021 - 01/2016
5Hypertension (High Blood Pressure)
01/2021 - 03/2017
5Glioma (Gliomas)
10/2019 - 01/2018
5Glioblastoma (Glioblastoma Multiforme)
01/2019 - 03/2017
5Alzheimer Disease (Alzheimer's Disease)
01/2019 - 01/2012
5Infections
01/2016 - 02/2007
5Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
05/2009 - 06/2005
4Neoplasm Metastasis (Metastasis)
05/2021 - 01/2018
4Heart Failure
01/2020 - 03/2007
4Carcinoma (Carcinomatosis)
09/2010 - 08/2002
3Rheumatoid Arthritis
07/2022 - 01/2002
3Knee Osteoarthritis
02/2022 - 07/2008
3Sepsis (Septicemia)
07/2021 - 01/2018
3Brain Death (Brain Dead)
04/2020 - 01/2020
3Cardiotoxicity
12/2019 - 05/2011
3Lung Neoplasms (Lung Cancer)
01/2018 - 07/2004
3Carcinogenesis
01/2018 - 01/2014
3Cardiomyopathies (Cardiomyopathy)
05/2012 - 05/2011
3Solitary Kidney
02/2009 - 04/2007
2Disease Progression
10/2022 - 01/2011
2Heart Arrest (Cardiac Arrest)
08/2021 - 05/2011

Drug/Important Bio-Agent (IBA)

18Reactive Oxygen Species (Oxygen Radicals)IBA
11/2021 - 09/2003
16Proteins (Proteins, Gene)FDA Link
07/2022 - 07/2004
151-phenyl-3,3-dimethyltriazene (PDT)IBA
02/2016 - 08/2002
14Pharmaceutical PreparationsIBA
01/2019 - 10/2003
12Biological ProductsIBA
06/2022 - 07/2010
11Cytochromes c (Cytochrome c)IBA
01/2022 - 07/2004
10CalciumIBA
08/2021 - 01/2007
9Amobarbital (Amsal)IBA
01/2018 - 01/2006
7Biomarkers (Surrogate Marker)IBA
12/2021 - 03/2013
7MicroRNAs (MicroRNA)IBA
01/2021 - 01/2014
7BuffersIBA
10/2020 - 01/2014
6CalpainIBA
12/2022 - 12/2011
6Long Noncoding RNAIBA
12/2021 - 01/2018
6Transcription Factors (Transcription Factor)IBA
05/2021 - 08/2011
6Adenosine Triphosphate (ATP)IBA
02/2019 - 06/2002
5Circular RNAIBA
07/2022 - 01/2021
5Messenger RNA (mRNA)IBA
01/2021 - 05/2009
5Metformin (Glucophage)FDA LinkGeneric
01/2021 - 12/2017
5Cisplatin (Platino)FDA LinkGeneric
01/2021 - 07/2010
5LipidsIBA
09/2020 - 03/2007
5Doxorubicin (Adriamycin)FDA LinkGeneric
12/2019 - 04/2006
5Cardiolipins (Cardiolipin)IBA
01/2017 - 07/2004
5Photosensitizing Agents (Photosensitizers)IBA
11/2015 - 10/2002
5Electron Transport Complex IV (Cytochrome c Oxidase)IBA
02/2014 - 07/2004
5NAD (NADH)IBA
10/2009 - 07/2002
5RotenoneIBA
02/2008 - 09/2003
5palladium-bacteriopheophorbideIBA
12/2007 - 10/2002
5Sevoflurane (Ultane)FDA LinkGeneric
02/2003 - 07/2002
4Mitochondrial Permeability Transition PoreIBA
01/2022 - 03/2011
4Therapeutic UsesIBA
05/2021 - 11/2015
4Apoptosis Inducing FactorIBA
10/2020 - 06/2013
4DNA (Deoxyribonucleic Acid)IBA
11/2016 - 02/2007
4Inosine Triphosphate (ITP)IBA
05/2009 - 06/2005
4Anesthetics (Anesthetic Agents)IBA
02/2003 - 07/2002
3dicarboxydine (DCD)IBA
01/2022 - 01/2020
3EnzymesIBA
01/2022 - 03/2011
3AntioxidantsIBA
02/2021 - 11/2015
3Oxygen (Dioxygen)IBA
01/2021 - 08/2002
3oxidized low density lipoproteinIBA
01/2021 - 01/2017
3Indicators and Reagents (Reagents)IBA
10/2020 - 07/2008
3AntigensIBA
01/2020 - 02/2016
3salicylhydroxamic acid (SHAM)IBA
12/2019 - 03/2002
3CytokinesIBA
03/2019 - 01/2013
3Neuroprotective AgentsIBA
01/2018 - 01/2014
3Phospholipids (Phosphatides)FDA LinkGeneric
01/2017 - 07/2004
3Folic Acid (Vitamin M)FDA LinkGeneric
02/2016 - 07/2012
3AcidsIBA
02/2016 - 06/2002
3STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
11/2015 - 08/2011
3GadoliniumIBA
10/2013 - 05/2007
3Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA
09/2012 - 02/2008
3Interleukin-1 (Interleukin 1)IBA
01/2011 - 09/2007
3Dihematoporphyrin Ether (Porfimer Sodium)FDA Link
08/2010 - 08/2002
3Protein Kinase CIBA
03/2006 - 06/2005
35-hydroxydecanoic acidIBA
02/2003 - 10/2002
2Testosterone (Sustanon)FDA Link
01/2022 - 01/2020
2UbiquitinIBA
01/2022 - 12/2020
2Bevacizumab (Avastin)FDA Link
12/2021 - 10/2019
2Mitochondrial DNA (mtDNA)IBA
09/2021 - 01/2018

Therapy/Procedure

25Therapeutics
10/2022 - 10/2002
13Drug Therapy (Chemotherapy)
03/2022 - 04/2006
10Photochemotherapy (Photodynamic Therapy)
02/2016 - 08/2002
5Transplantation
01/2022 - 10/2006
5Lasers (Laser)
11/2015 - 08/2002
3Radiotherapy
05/2021 - 06/2004
3Heart Transplantation (Grafting, Heart)
01/2021 - 01/2020